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Trends in statin use 2009–2015 in a large integrated health system: Pre- and post-2013 ACC/AHA guideline on treatment of blood cholesterol

Cardiovascular Drugs and Therapy Aug 02, 2018

Harrison TN, et al. - Among members of Kaiser Permanente Southern California aged ≥ 21 years, a retrospective study with annual cohorts from 2009 to 2015 was conducted to explore trends in statin use before and after the introduction of the American College of Cardiology/American Heart Association guidelines. Researchers reported that trends in statin use were stable for adults with atherosclerotic cardiovascular disease (ASCVD), recent low-density lipoprotein cholesterol (LDL-C) ≥ 190 mg/dL, and diabetes, but increased for patients with 10-year ASCVD risk ≥ 7.5%. High-intensity statin use also increased 142% among patients with LDL-C ≥ 190 mg/dL and 54% among those with ASCVD ≤ 75 years of age. Among those with a 10-year ASCVD risk ≥ 7.5%, moderate-to-high intensity statin utilization increased over 50%.

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