Syrigos N, et al. - In this study, the response patterns of patients having refractory chronic spontaneous urticaria (CSU) managed with omalizumab were evaluated in a real-world clinical setting. Data illustrated that omalizumab, either alone or in combination with a short-term course of corticosteroids, was highly effective in the resolution of refractory CSU. It was also deduced that the disease duration prior to omalizumab exerted a prominent impact on the timing of the response.