Kessels JPHM, et al. - This research analyzed the superiority of 2-fold 5-aminolevulinic acid (ALA)-photodynamic therapy (PDT) compared to conventional methyl-ester (MAL)-PDT for superficial basal cell carcinoma (sBCC). This approach displayed fewer recurrences, despite the lack of prominent variation between both the treatment groups. It, however, led to higher pain scores and more post-treatment side-effects compared to MAL-PDT.