Demirci GK, et al. - The present study prospectively assessed and compared the impact of various predictors on results of apexification utilizing either mineral trioxide aggregate (MTA) or calcium hydroxide (CH) in permanent immature anterior teeth with necrotic pulps and periapical lesions of adults. Between 2015 and 2018, 90 immature teeth with necrotic pulps and periapical lesions on adult patients, aged 18 to 40 years, were treated with MTA (45 teeth) or CH (45 teeth). Of the 45 teeth treated with MTA, 39 were accessible for recall. According to findings, similar treatment outcomes were associated with apexification treatment with MTA and CH. Due to the shorter treatment time associated with its use, MTA can be proposed as a material for apexification treatment in adult patients' immature teeth.