Saint GL, Thomas MF, Abidin NZ, et al. - Data of a multicenter cohort of children with cystic fibrosis (CF) in the UK were analyzed to describe the approaches to diagnosis, management and consequences of treatment in this population.

• From 11 CF specialist centres, researchers obtained data of 70 patients who were treated for nontuberculous mycobacteria (NTM) pulmonary disease (60 Mycobacterium abscessus complex (MABSC); 10 M. avium complex (MAC)).

• NTM was observed in significant association with older age as well as with previous diagnosis of allergic bronchopulmonary aspergillosis.

• Drug choice varied widely and all agents were linked with side effects.

• 80% of patients with MAC and 48% with MABSC showed mycobacterial eradication, with variable outcomes on lung function.

• Overall findings support that it is challenging to diagnose and treat NTM infection in children with CF.

• There is no surety that treatment will be successful, particularly for MABSC.