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Transoral laser microsurgery and radiotherapy for oropharyngeal squamous cell carcinoma: Equitable survival and enhanced function compared with contemporary standards of care

European Journal of Surgical Oncology Sep 08, 2020

Dalton CL, Milinis K, Houghton D, et al. - Researchers sought to report on the 5-year oncological and functional outcomes of transoral laser microsurgery, neck dissection (TLM + ND) and adjuvant radiotherapy (PORT) employed to manage patients with oropharyngeal carcinoma. In addition, they reported on the effectiveness of external carotid artery (ECA) ligation in annihilating postoperative bleeding, and fibrin glue following ND in decreasing wound drainage and length of hospital stay. They retrospectively reviewed 264 consecutive patients undergoing TLM between 2006 and 2017. Among these patients, 219 (82.9%) patients underwent PORT. Outcomes revealed achievement of favourable 5-year survival and locoregional control rates, and low feeding tube dependency rates in correlation with receiving TLM + ND + PORT. Major postoperative hemorrhage, wound drainage and length of hospital stay seemed reducing with using ECA ligation and fibrin glue.

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