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Trace minerals, heavy metals, and preeclampsia: Findings from the Boston Birth Cohort

Journal of the American Heart Association Aug 26, 2019

Liu T, Zhang M, Guallar E, et al. - Given that manganese (Mn) and selenium (Se) were protective and cadmium (Cd) was promotive for preeclampsia in mice experiments, researchers intended to corroborate these findings by assessing preeclampsia in relation to trace minerals (Mn and Se) and heavy metals (Cd, lead [Pb], and mercury [Hg]) in the Boston Birth Cohort. Among those with complete data available on the exposures and outcome, 1,274 women were included. From red blood cells obtained within 24 to 72 hours following delivery, Mn, Se, Cd, Pb, and Hg were measured. In line with the evidence from mice experiments and human studies, the findings of this study revealed a higher likelihood of developing preeclampsia for women with a lower blood level of Mn or a higher blood level of Cd.

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