di Laura Frattura G, et al. - Via a systematic literature review, the researchers intended to examine factors affecting proprioception in 676 individuals with knee osteoarthritis (OA) who underwent total knee arthroplasty (TKA). A total of 1,601 records were recognized. Post-surgery, proprioception was observed as generally improving but often lasting as impaired. Powerful evidence was obtained for no impact of prosthesis design on proprioception. For patellar resurfacing not influencing proprioception, varus deformity negatively impacting proprioception, and time passed from surgery positively affecting proprioception, moderate evidence was discovered. Also, limited data was attained for valgus deformity, OA grade, intact anterior cruciate ligament, and anteroposterior joint laxity negatively influencing knee proprioception, and for muscle strength and sensorimotor training not influencing proprioception. For better postoperative proprioception, contrasting evidence was discovered in comparison with the preoperative level. Hence, proprioception in OA patients who underwent TKA improved, however, it remained impaired post-surgery. The best evidence synthesis exhibited no influence of prosthetic design, however, the unclear role of the treatment was observed. Moreover, in order to analyze proprioceptive impairment for better management of OA patients undergoing TKA, further research efforts are guaranteed.