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Torsemide vs furosemide after acute decompensated heart failure: A retrospective observational study

BMC Cardiovascular Disorders Jun 04, 2019

Rahhal A, et al. - Using Cox proportional hazard regression, researchers assessed how heart failure (HF)-related hospitalization within 1 month and 6 months of discharge was influenced by switching furosemide to torsemide vs optimizing the furosemide dose post-acute decompensated heart failure (ADHF). The patients examined had previously received furosemide. Upon discharge, torsemide and an optimized furosemide dose were received by 45 and 187 patients, respectively, of the overall study sample of 232 patients. With a mean age of 67 ± 12 years, and male predominance (54%), the study sample had HF with reduced ejection fraction (57%) at presentation and a history of coronary artery disease (68%). No reduced HF-related hospitalization was reported in relation to switching furosemide to torsemide after ADHF vs receiving an optimized furosemide dose.
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