Borrelli E, et al. - Authors studied the macular microvascular networks in patients affected by chronic Leber’s hereditary optic neuropathy (LHON) using optical coherence tomography angiography (OCTA). They also quantified these changes in different macular sectors. SCP and DCP changes which are mainly confined to the nasal and inferior parafoveal sectors that correspond to the papillomacular bundle were seen in LHON eyes. Moreover, experts noted an association of visual loss with the SCP flow impairment, but not with the OCT-detectable structural damage.