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Time course of relapse following acute treatment for anorexia nervosa

American Journal of Psychiatry Jun 27, 2021

Walsh BT, Xu T, Wang Y, et al. - In order to best define the stages of illness for anorexia nervosa, including remission and recovery, researchers herein investigated the time course of relapse over the year following full weight restoration using a previously published study. In an acute care setting, 93 women with anorexia nervosa were randomized to receive fluoxetine or placebo following weight restoration; these women were discharged to outpatient care, where they received cognitive-behavioral therapy, in addition, for up to 1 year. Findings suggest an elevated risk of relapse among adult patients with anorexia nervosa in the first months following discharge from acute care, highlighting the necessity for frequent follow-up and relapse prevention–focused treatment during this period. After nearly 2 months, a progressive decrease in the risk of relapse occurs over time.

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