Jadhav AP, Goyal M, Ospel J, et al. - Among patients treated for acute ischemic stroke, similar rates of good functional outcome were found among those in whom computed tomography perfusion (CTP) was or was not performed. Also, endovascular thrombectomy (EVT) treatment impact in the 0- to 6-hour time window was found to be similar in cases with and without baseline CTP imaging.

• From randomized controlled trials comparing EVT with usual care for acute ischemic stroke due to anterior circulation large vessel occlusion, patient-level data were pooled.

• Experts analyzed 1,348 patients, 610 (45.3%) of whom had CTP prerandomization.

• The advantage of EVT vs best medical management was shown to be maintained regardless of the baseline imaging paradigm (90-day modified Rankin Scale score 0–2 in EVT vs control patients: with CTP: 46.0% (137/298) vs 28.9% (88/305), without CTP: 44.1% (162/367) vs 27.3% (100/366).

• Similar rates of good outcome were achieved with CTP baseline imaging vs baseline noncontrast computed tomography [CT] and CT angiography only (odds ratio, 1.05, adjusted odds ratio, 1.04).