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Three-year active surveillance outcomes in a contemporary community urology cohort in the United States

Urology Jul 27, 2019

Shelton JB, et al. - Outcomes for 548 men diagnosed between January 1, 2013, and May 31, 2014, with National Comprehensive Cancer Network (NCCN) very low, low and intermediate-risk prostate cancer who selected active surveillance (AS, is the management of choice for a majority of men with lower-risk prostate cancer) in 9 large community urology practices were retrospectively assessed by the researchers in order to determine the 3-year outcomes of men with prostate cancer managed with AS. About 89% (492) proceeded to follow-up with diagnosing practice and 32% (171) discontinued AS. Rising NCCN risk classification was significantly correlated with discontinuation on multivariate analysis. Surgery and radiation were used proportionately amongst those who discontinued AS. Hence, a minority was lost to follow-up and adherence to AS was alike to other reports in this community-based cohort of men on AS. Disease features more than sociodemographic features associated with adherence to AS, whereas surgery and radiotherapy were used equitably among those who discontinued AS, both implying the guideline-concordant practice of medicine.
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