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Three-dimensional visualisation of the fetal heart using prenatal MRI with motion-corrected slice-volume registration: A prospective, single-centre cohort study

The Lancet Mar 29, 2019

Lloyd DFA, et al. - For congenital heart disease diagnosis, researchers examined prenatal MRI combined with novel, motion-corrected three-dimensional (3D) image registration software as an adjunct to fetal echocardiography. A tertiary fetal cardiology unit recruited pregnant women carrying a fetus with known or suspected congenital heart disease. One hundred one patients were referred for MRI between October 8, 2015 and June 30, 2017, of which 85 were eligible and had fetal MRI. According to findings, a dependable way of producing high-resolution 3D imaging of the fetal vasculature was seen with standard fetal MRI with open-source image processing software. Compared to source two-dimensional (2D) MRI data, the 3D volumes show good ultrasound spatial agreement and significantly improved visualization and diagnostic quality. This is the largest study investigating the use of prenatal MRI in congenital heart disease fetuses, which concluded that this combination involves minimal infrastructure and provides safe, powerful and highly complementary imaging to the fetal cardiovascular system.

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