Allegrini D, et al. – The contribution of vascular volume calculated by optical coherence tomography angiography (OCTA) to the measurement of peripapillary retinal nerve fibre layer (RNFL) thickness is explored in this study. They found that the vascular contribution to the RNFL thickness is 29.07±3.945%. This is much higher than what has been reported from calculations made on the structural OCT alone (13% reported by Hood et al and 11.3%±1.6% for the Cirrus OCT and 11.8%±1.4% for the Spectralis OCT reported by Patel et al). They conclude that assessment of the vascular tissue contribution to the RNFL thickness with OCTA could be valuable when performing precise quantification of the neuronal tissue.