Bergamaschi L, D’Angelo EC, Paolisso P, et al. - Whether serial electrocardiograms have prognostic value in patients suffering from coronavirus disease 2019 (COVID‐19), was investigated herein. Participants were 269 consecutive patients admitted with proven Severe Acute Respiratory Syndrome Coronavirus‐2 infection. Evaluation of ECGs, available at admission as well as after 1 week from hospitalization, was done. Experts assessed if and how ECGs findings were correlated with major adverse events (MAE; defined as the composite of intra‐hospital all‐cause death or requirement for invasive mechanical ventilation). A significant association of ischemic alterations as well as of left ventricular hypertrophy, among abnormal ECGs, with a higher MAE rate was found. In multivariable analysis, MAE was independently predicted by the presence of abnormal ECG at 7 days of hospitalization. The need for transfer to the intensive care unit or renal replacement therapy was often more in cases with abnormal ECG at 7 days. Overall, experts concluded that ECG should be received by COVID‐19 patients both at admission and during hospital stay. Definitely, electrocardiographic changes during hospitalization were identified to be related to MAE and infection severity.