McDonald LK, et al. - This study attempted to explore the efficacy and safety of the Ligament Augmentation and Reconstruction System (LARS) in posterior cruciate ligament (PCL) reconstruction in isolated PCL injuries and multiligament knee injuries, analysing clinical, radiographic, and patient reported outcome measures (PROMs). Researchers conducted a systematic review according to PRISMA guidelines through Embase via Ovid, PubMed, and the Cochrane Library to identify studies reviewing LARS use for PCL reconstruction. The Methodological Index for Non-Randomized Studies (MINORS) criteria were used to evaluate the methodological quality. From 225 results screened, between 2004 and 2020, 13 studies were published, analysing LARS use for PCL reconstruction. In PCL injury reconstruction, LARS demonstrates good outcomes in the short to mid-term, especially in isolated PCL injuries, achieving equivocal or improved results in comparison with autograft reconstruction using hamstring tendon in the three comparative studies included. As per the findings, LARS has a quicker recovery time and no donor-site morbidity, nevertheless long-term data is lacking. In multiligament injuries, applying LARS for reconstruction of the PCL revealed more variable results.