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The Urinary Uric Acid / Cr ratio as a marker of morbidity and mortality of preterm infants: A case-control study

BMC Pediatrics Jul 28, 2021

Sadeghzadeh M, Khoshnevisasl P, Fallah R, et al. - Researchers conducted this case-control study to explore the connection between the Urinary Uric Acid / Cr (UUA/Cr) ratio and outcomes of preterm infants admitted to neonatal intensive care unit (NICU). The sample consisted of 102 preterm newborn infants with gestational age of 30 weeks to 33 weeks and 6 days admitted in the NICU. The case group, which included 51 premature neonates who had a history of intubation, cardiopulmonary resuscitation, mechanical ventilation, and nasal continuous positive airway pressure (NCPAP) at birth, were compared with a control group of 51 neonates. The mean levels of UUA/Cr ratio in the case and control groups were 5.4 ± 4.1 and 3.6 9 ± 2.9, respectively, with a statistically significant difference. The UUA/Cr ratio was higher in preterm neonates who underwent intubation, NCPAP, or cardiopulmonary resuscitation in the first 24 h after birth than in healthy neonates.

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