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The transmissibility of antibiotic-resistant Enterobacteriaceae in Intensive Care Units

Clinical Infectious Diseases Oct 04, 2017

Gurieva T, et al. - Authors performed this post-hoc analysis of a multicenter study in 13 European intensive care units (ICUs) prospective surveillance data and used a mathematical model to determine transmission capacities and single admission reproduction numbers (RA) of Escherichia coli and non-E. coli Enterobacteriaceae, all being expanded-spectrum cephalosporins (ESCs)-resistant. In ICUs non-E. coli Enterobacteriacea (non-EcE), mainly being K. pneumoniae, were 3.7 times more transmissible than E.coli. Estimated RA values of these bacteria were below the critical threshold of one, suggesting that in these ICUs outbreaks typically remain small with current infection control policies.
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