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The role of nasal endoscopy in allergic rhinitis and house dust mite sublingual immunotherapy

International Archives of Allergy and Immunology May 21, 2021

Liu B, et al. - In this study with 105 patients with allergic rhinitis (AR) caused by house dust mites, researchers assessed the therapeutic impact of sublingual immunotherapy (SLIT). For this purpose, they conducted endoscopic examination and the modified Lund-Kennedy (MLK) scoring system. Participants received treatment with standardized Dermatophagoides farinae (D. farinae) drops for 1 year. Following SLIT, a statistical reduction in total nasal symptoms score (TNSS), total medication score (TMS), and visual analog scale (VAS) scores was evident relative to baseline. On nasal endoscopy examination, there were significant improvements in nasal signs, which primarily included color change of turbinate mucosa, decrease of nasal secretions, and improvement of nasal edema. Findings of endoscopic analysis and the MLK scores, in addition to commonly used subjective evaluations (TMS, TNSS, and VAS), consistently corroborated the effectiveness of SLIT as a therapeutic choice for AR patients. MLK scores might be regarded as an auxiliary instrument to assess SLIT’s efficacy in clinical practice and outcomes research.

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