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The risk of human papillomavirus infection for spontaneous abortion, spontaneous preterm birth, and pregnancy rate of assisted reproductive technologies: A systematic review and meta-analysis

Gynecologic and Obstetric Investigation Apr 17, 2018

Xiong YQ, et al. - Researchers aimed at determining the impact of human papillomavirus (HPV) infection on spontaneous abortion, spontaneous preterm birth (sPTB), pregnancy rate of females undergoing assisted reproductive technologies (ART), and spontaneous abortion of ART pregnancy. An increased risk of spontaneous abortion was noted with indiscriminate HPV genotype infection. High-risk HPV [HR-HPV] infection was noted as a risk factor for sPTB. However, they did not identify enough evidence to indicate the association between HPV infection and pregnancy rate of ART, and spontaneous abortion of ART pregnancy. Different genotypes of HPV infection could have a discrepant role in adverse pregnancy outcomes.
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