Mazidi M, et al. – In this current study performed on US adults, the link between plasma trans fatty acids (TFAs) and the dietary inflammatory index (DII) was assessed. According to findings of this investigation, a link between plasma TFAs and a marker of dietary inflammation indicated an underlying mechanism in the initiation and progression of cardiovascular diseases.

Methods

• This study included participants from National Health and Nutrition Examination Survey (NHANES) with data on plasma TFAs measured from 1999 to 2010.
• Energy-adjusted-DII (E-DII ) expressed per 1000 kcal was calculated from 24-h dietary recalls.
• All statistical analyses accounted for the survey design and sample weights.

Results

• Findings demonstrated that out of the 5446 eligible participants, 46.8% (n = 2550) were men.
• Researchers found that the mean age of the population was 47.1 years overall, 47.8 years for men and 46.5 years for women (p = 0.09).
• Results also revealed that after adjustment for C-reactive protein, body-mass-index, smoking, race, age, education, and marital status in linear regressions, trans 9-hexadecenoic acid [β coefficient 0.068 (95% CI: 0.032 to 0.188)], trans 11-octadecenoic acid [β coefficient 0.143 (95% CI: 0.155 to 0.310)], trans 9-octadecenoic acid [β coefficient 0.122 (95% CI: 0.120 to 0.277)], trans 9, and trans 12-octadienoic acid [β coefficient 0.103 (95% CI: 0.090 to 0.247)] were positively associated with the DII (allp < 0.001).