Weber F, Rashmi BK, Karaoz‐Bulut G, et al. - Among spontaneously breathing anesthetized children, whether the Pleth Variability Index has predictive value as a measure of fluid responsiveness was investigated in this study. During anesthesia induction in 50 pediatric patients < 6 years, experts recorded Pleth Variability Index, stroke volume and Cardiac Index, determined by electrovelocimetry, mean blood pressure, and heart rate. They performed comparison between baseline values and values obtained following administration of 10 mL/kg of Ringer's lactate and during two passive leg raising tests (prior to and following fluid administration). A rise of ≥ 10% in stroke volume defined fluid responsiveness. Based on the findings, experts concluded likely additional value of the Pleth Variability Index to predict fluid responsiveness in spontaneously breathing anesthetized children. A reliable recommendation as to a cut off value was not permitted by a significant overlap in baseline Pleth Variability Index values between fluid responsive and nonfluid responsive patients.