Sato R, Hasegawa D, Hamahata NT, et al. - Since there exists a controversy regarding the predictive worth of airway occlusion pressure at 100 milliseconds (P0.1) on weaning outcome, therefore, researchers examined the predictive value of P0.1 on successful weaning from mechanical ventilation in this meta-analysis. This analysis involved 12 prospective observational studies (n = 1,089 patients) which were identified from MEDLINE, Cochrane Central Register of Controlled Trials, and EMBASE. An area under the curve of 0.81 for P0.1 was generated in analyses of summary receiver operating characteristic curves. The pooled sensitivity and specificity were estimated to be 86% and 58% with substantial heterogeneity respectively. Based on the findings, the usefulness of P0.1 as an instrument to predict successful weaning was indicated. A large prospective analysis exploring the sensitivity as well as the specificity of P0.1 on weaning results from mechanical ventilation is warranted in order to ascertain the clinical utility.