Strand K, Søreide E, Kirkegaard H, et al. - Given the common occurrence of acute kidney injury (AKI) after cardiac arrest and targeted temperature management (TTM), researchers sought to assess how different lengths of cooling influence the development of AKI. They conducted a sub-study of the TTH48 trial, which involved patients cooled to 33 ± 1 ˚ ° C following an out-of-hospital cardiac arrest for 24 vs 48 hours. The KDIGO AKI criteria based on serum creatinine and urine output collected until ICU discharge for a maximum of seven days were used to classify AKI. They included 349 patients in the study; of these, 159 (45.5%) developed AKI. This indicates AKI prevalence in almost half of all ICU admitted patients following cardiac arrest and TTM. Findings revealed no association between prolonged TTM at 33 °C and the risk of AKI during the first seven days in the ICU. AKI occurs more commonly in the elderly, with an increasing BMI and longer arrest duration. They identified AKI after cardiac arrest as an independent predictor of time to death.