Yoshida M, Yabuuchi Y, Kakushima N, et al. - Using a large‐scale national database, researchers sought to illustrate the incidence and clinical features of duodenal cancer in Japan. Data were collected from the Japanese national cancer registry for patients with primary duodenal cancer diagnosed from January 1, 2016 to December 31, 2016. Data on 3,005 patients were involved. The authors discovered that duodenal cancer incidence was 23.7 per 1,000,000 person‐years. There were 56.4% of cases identified at the localized stage. Independent risk factors for advanced cancer, as the multivariate analyses identified, were age ≥ 80 years, incidental detection, and precise examination for symptomatic patients. The study showed the incidence of duodenal cancer in Japan. The major tumor stage when it was found, was localized cancer, leading to a high rate of endoscopic resection.