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The impact of severe mental illness on lung cancer mortality of patients with lung cancer in Finland in 1990–2013: A register-based cohort study

European Journal of Cancer Aug 14, 2019

Arffman M, Manderbacka K, Suvisaari J, et al. - Patients with lung cancer with and without a history of severe mental illness (SMI) were compared regarding cancer-specific mortality. In addition, researchers analysed if cancer stage at presentation, comorbidity or differences in cancer treatment could explain their mortality differences. From the Finnish Cancer Registry, they identified 37,852 lung cancer cases in 1990–2013 including 12% with a history of SMI. Persons with a history of SMI showed elevated cancer-specific mortality. Excess mortality risk was observed for men with a history of psychosis in squamous cell carcinoma. Women with psychosis showed similar excess risk in small-cell carcinoma and in squamous cell carcinoma and women with mood disorders showed the excess risk in adenocarcinoma. No marked change in patient group differences in HRs in 5-year mortality was observed from the 1990s. Collaboration between patients, mental healthcare professionals and oncological teams is needed to reduce the mortality gap between patients with cancer with and without SMI. To reduce the mortality gap between patients with cancer with and without SMI, they suggest collaborating patients, mental healthcare professionals, and oncological teams.
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