Saglam F, Baysal O, Sofulu O, et al. - The present study was conducted to assess the effect of pathological fractures on surgery, morbidity, functional and oncological outcomes in patients with primary bone sarcomas. Between 2005 and 2019, researchers conducted a retrospective analysis of 568 patients with primary bone sarcomas, treated. The research enrolled 41 individuals with a pathological fracture and 51 control patients who did not have a pathological fracture. They used a multivariate Cox regression analysis to evaluate the impact of pathological fractures and further independent variables on the amount of intraoperative bleeding, duration of surgery, the number of muscles and major neurovascular structures included in resection, tumor volume, surgical volume, Musculoskeletal Tumor Society functional score, postoperative complication rate, and local recurrence, distant metastasis, and survival rates. It was shown that a pathological fracture through a primary bone sarcoma has no adverse effect on prognostic factors such as local recurrence, distant metastasis, and survival. Nevertheless, in addition to reduced functional outcomes, pathological fractures increase the amount of intraoperative bleeding and surgical volume and result in a longer surgery.