Tanacan A, Yazihan N, Erol SA, et al. - Pregnant women with confirmed coronavirus disease (COVID-19) infection (study group) (n = 90) were prospectively compared with pregnant women without any defined risk factor (n = 90), with respect to the levels of various cytokines. Findings revealed significantly higher pregnancy complication rate, erythrocyte sedimentation rate, C-reactive protein, procalcitonin, ferritin, D-dimer, lactate dehydrogenase, IFN γ, and IL-6 values in the study group, whereas, the control group exhibited significantly higher hemoglobin, leukocyte, platelet, lymphocyte, IL-2, IL-10, and IL-17 values. The groups exhibited statistically significant differences in terms of IFN γ, IL-2, IL-10, and IL-17 values between the trimesters. Researchers noted statistically significant positive correlations for IFN γ and IL-6 with disease severity. On the other hand, there was a moderate negative correlation for IL-2 and a weak negative correlation for IL-10. IL-6 and CRP were identified to have a statistically significant positive moderate correlation. These findings are suggestive of an impact of COVID-19 infection on the cytokine profile of pregnant women, which varies according to pregnancy trimesters, and of the correlation of cytokine levels with disease severity.