Elmunzer BJ, et al. – The physicians evaluated the effect of cholecystectomy after endoscopic sphincterotomy (ES) among elderly patients, in whom the perceived risks of surgery may be increased and the prevailing bias may be to defer cholecystectomy. Compared to sphincterotomy alone, cholecystectomy after endoscopic sphincterotomy was correlated with a significant and clinically important reduction in recurrent complications among older patients, including those with serious comorbidities. This benefit did not seem to be outweighed by surgical complications even in elderly patients whose lifespans could be limited by unrelated conditions underscoring the importance of cholecystectomy.