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The hemoglobin glycation index is associated with non-alcoholic fatty liver disease in healthy subjects

Clinical Endocrinology May 08, 2019

Yoo JH, et al. - In a healthy Korean cohort of 14,465 subjects, researchers examined the connection between hemoglobin glycation index (HGI) and non-alcoholic fatty liver disease (NAFLD). With each HGI quartile, NAFLD's prevalence increased significantly. Individuals in the highest quartile showed worse metabolic parameters, including body weight, waist circumference, body mass index, and lipid profiles vs those in the lowest HGI quartile. Upon adjusted for multiple factors, multiple logistic regression analysis revealed that the odds ratio of having NAFLD was 1.564 in the highest HGI quartile. Overall, in this healthy Asian population, elevated levels of HGI were independently linked to NAFLD.

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