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The expression and correlation of Hsp 70 and Hsp 27 in serous middle ear effusion fluids of pediatric patients-A preliminary study

International Journal of Pediatric Otorhinolaryngology Aug 16, 2017

Min HJ, et al. – The researchers explored the role of heat shock proteins (Hsps) in the development of otitis media with effusion (OME). They reported that Hsp 70 and Hsp 27 were expressed in middle ear effusions. Moreover, the levels of Hsp 70 and Hsp 27 were positively associated with each other and were also positively associated with the neutrophil chemoattractant, IL–8. These findings indicated that Hsp 70 and Hsp 27 were probably involved in the pathophysiology of pediatric OME.
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