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The epidemiology of psoriatic arthritis over five decades: A population‐based study

Arthritis & Rheumatology Aug 19, 2021

Karmacharya P, Crowson CS, Bekele D, et al. - The results indicated that in this predominantly White US population, the incidence of psoriatic arthritis (PsA) was stable in 2000–2017, in contrast to previous years. Nevertheless, researchers observed an increasing proportion of women with PsA in this study.

  • Researchers included 164 incident cases of PsA in 2000–2017 (mean ± SD age 46.4 ± 12.0 years; 47% female).

  • According to the findings, 8.5 was the overall age- and gender-adjusted annual incidence of PsA per 100,000 population (95% confidence interval [95% CI] 7.2–9.8) and was higher in men (9.3 [95% CI 7.4–11.3]) than women (7.7 [95% CI 5.9–9.4]) in 2000–2017.

  • In the 40–59 years age group, the overall incidence was highest.

  • During 2000–2017, the incidence rate was relatively stable, with no evidence of an overall increase or an increase in men only (but a modest increase of 3% per year in women), compared to 1970–1999 when a 4%-per-year increase in incidence was observed.

  • In 2015, point prevalence was 181.8 per 100,000 population (95% CI 156.5–207.1).

  • It was shown that the percentage of women among those with PsA increased from 39% in 1970–1999 and 41% in 2000–2009 to 54% in 2010–2017 (P = 0.08).

  • In PsA, overall survival did not differ from the general population (standardized mortality ratio 0.85 [95% CI 0.61–1.15]).

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