Chen XT, Fang W, Jones IA, et al. - This study was attempted to evaluate the effectiveness of platelet-rich plasma (PRP) for lateral epicondylitis and assess its effect on pain and functional outcomes. Researchers performed a comprehensive literature search in September 2019 and repeated it in April 2020 using electronic databases PubMed, MEDLINE, and the Cochrane Library. Sixteen level I studies were included in this review, 9 (581 total patients, 281 receiving single injections of PRP) of which were quantitatively examined. According to the findings, considering the small number of comparable studies, lack of quantification of specific PRP content, considerable heterogeneity between each RCT, and that most effect sizes were equivocal within the framework of two estimated minimal clinically important difference values, despite finding statistically significant improvements in pain and functional outcomes, the authors can neither scientifically support nor discourage the usage of PRP for lateral epicondylitis.