Banerjee S, et al. - In a pediatric population with steroid-sensitive nephrotic syndrome (NS), researchers assessed 25-hydroxycholecalciferol (25(OH)D) levels, bone mineralization, and NS relapse rate following vitamin D3 and calcium supplementation. Over a 6-month follow-up, no changes were seen in bone mineral content (BMC), bone mineral density (BMD) or relapse rate but 25(OH)D levels were found to be significantly improved as a result of supplementation with calcium and vitamin D. Notably while using such therapy, occurrence of hypercalciuria mandates caution and appropriate monitoring. There remained uncertainty regarding appropriate dosage of vitamin D3.