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The effect of umbilical cord blood spexin, free 25(OH) vitamin D3 and adipocytokine levels on intrauterine growth and anthropometric measurements in newborns

Cytokine May 25, 2021

Sanli S, et al. - Researchers assessed how spexin and adipocytokin levels in the cord blood of term newborn babies could impact weight of the baby based on the gestation age (GA) and anthropometric measurement results. They analyzed babies who were born in their hospital and whose GA was ≥ 37 weeks, split into three groups as appropriate for GA (AGA), small for GA (SGA) and large for GA (LGA). With respect to mean spexin, active ghrelin, free 25(OH) vitamin D3, and insulin levels, no statistically significant difference was observed between groups. Significantly higher mean leptin level was found in LGA group vs SGA and AGA groups. Girls vs boys were identified to have higher mean spexin and leptin levels. A significant positive correlation was evident between birth weight, head circumference, height, umbilical circumference, umbilical circumference/height ratio and the mean leptin concentrations, but no significant correlation existed between mean spexin, active ghrelin, free 25 (OH) vitamin D3, insulin, and glucose concentrations. Likely, intrauterine development is not influenced by spexin.

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