Steen DL, et al. - Researchers presumed that the post-acute coronary syndrome (ACS) period would minimally influence the impact of fasting status on lipid measurements. In this study, an impact of fasting on lipid measurements was evident, though the effect on low-density lipoprotein cholesterol was small (about 4 mg/dL), this was noted both early after ACS and during follow-up. This work lends support to recent guidelines that no longer advocate for fasting lipid samples, including in the setting of ACS.