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The CD4/CD8 ratio of tumor-infiltrating lymphocytes at the tumor-host interface has prognostic value in triple negative breast cancer

Human Pathology Oct 12, 2017

Wang K, et al. - This research explored the role of the CD4/CD8 ratio of tumor-infiltrating lymphocytes (TILs) at the tumor-host interface in triple negative breast cancer (TNBC). Both the tumor size and nodal status displayed a prominent correlation with survival outcomes. The data yielded additional support for the contention that TILs, as a marker of regional immune escape, exhibited prognostic significance in TNBC progression and that the CD4/CD8 ratio of TILs at the tumor-host interface plays a distinctive role, thus appearing to be of clinical relevance.

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