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The causes of gastroesophageal reflux after laparoscopic sleeve gastrectomy: Quantitative assessment of the structure and function of the esophagogastric junction by magnetic resonance imaging and high-resolution manometry

Obesity Surgery May 08, 2020

Quero G, Fiorillo C, Dallemagne B, et al. - This study assessed how the structure and function of the esophagogastric junction (EGJ) and stomach are impacted by laparoscopic sleeve gastrectomy (LSG). Researchers investigated before and after > 50% reduction in excess body weight (6–12 months after LSG). They excluded individuals with gastroesophageal reflux disease (GERD) at baseline. Before and after LSG, they applied MRI, high-resolution manometry, and ambulatory pH-impedance measurements to evaluate the structure and function of the EGJ and stomach. A total of 35 patients were included in the study. Following surgery, esophageal acid exposure and reflux increased. The esophagogastric insertion angle and esophageal opening diameter were increased, while intrabdominal EGJ length and pressure were reduced. Changes in EGJ insertion angle correlated with an increase in reflux events. The highest prevalence of symptomatic GERD was seen in those with > 80% reduction in gastric capacity.

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