The C-reactive protein to albumin ratio predicts acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
Heart, Lung, and Circulation Sep 12, 2018
Karabag Y, et al. - In this review of 815 consecutive ST elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI), researchers investigated whether the C-reactive protein (CRP) to albumin ratio (CAR, a newly introduced inflammation-based risk score) was associated with acute kidney injury (AKI) development. They found that patients with AKI vs those without AKI had a higher in-hospital mortality rate. Compared with patients without AKI, those with AKI had significantly higher mean value of CRP and CAR and lower mean levels of albumin. Identified independent predictors of AKI included age, diabetes mellitus, hematocrit, left ventricular ejection fraction, hypotension, and CAR. Overall, in STEMI patients treated with pPCI, CAR may have utility as an inflammation-based risk score to predict AKI development.
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