Toraih E, Hussein M, Tatum D, et al. - Given a high risk for unplanned readmission in correlation with undergoing extensive surgical debridement with necrotizing soft tissue infections (NSTIs), researchers herein sought to determine the burden of readmission in patients afflicted with NSTI. Per their hypothesis, unplanned readmission would significantly contribute to the burden of disease following discharge from initial hospitalization. The Nationwide Readmission Database from 2010 to 2017 yielded data of a total of 82,738 NSTI admissions, of which 25,076 (30.3%) underwent 90-day readmissions. Following were identified as independent risk factors for readmission: fragmentation of care, longer length of index stay (> 2 weeks), and Medicaid status. A readmission cost on average US $10,543. Over the study period, readmission added 174,640 hospital days to episodes of care, leading to an estimated financial burden of US $1.4 billion. These findings suggest that unplanned readmission because of NSTIs is common and costly. The burden of disease may lower by implementing interventions that target patients at risk for readmission.