The association of adverse outcomes with pregnancy conception methods among low-risk term pregnancies
Fertility and Sterility Mar 26, 2021
Doty MS, Chen HY, Wagner SM, et al. - In this population-based retrospective cohort study, researchers compared composite neonatal and maternal adverse outcomes among low-risk singleton pregnancies at 37–41 weeks among conception methods: spontaneously-conceived (SC) pregnancy; infertility medications and/or intrauterine insemination (IFM/IUI); and assisted reproductive technology (ART). They analyzed low-risk pregnancies (without hypertensive disorders, pregestational or gestational diabetes, or history of preterm birth) of women ≥ 20 years who had nonanomalous singletons, labored, delivered at 37–41 weeks, and had information on pregnancy conception method. Data reported that the overall rate of composite neonatal adverse outcome was 6.68 per 1,000 live births. IFM/IUI and ART have modestly higher rates of adverse outcomes to maternal-neonatal dyad than SC in low-risk term singleton pregnancies.
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