Milan R, et al. - By conducting a secondary analysis on data for 137 individuals in the third wave of the Étude sur la Santé des Aînés–Services study (2015–2017) that included older adults aged 65 years and older, researchers determined how adherence to antidepressants is associated with self-reported side effects while bearing in mind their tolerability in these elderly patients. Adherence to antidepressants was reported in 69.3% of participants and non-adherence in 30.7%. Sleep disturbance, gastrointestinal system, and nervous system related side effects were noted in participants who were less likely to be adherent to their antidepressants. Palpitations were more likely among participants who adhere to their antidepressants. Non-tolerable nervous system-related side effects were reported in participants who were less likely to be adherent; non-tolerable gastrointestinal system-related side effects were reported in those with higher adherence to antidepressants.