Switching from low dose thiazide diuretics to SGLT2 inhibitor improves various metabolic parameters without affecting blood pressure in subjects with type 2 diabetes and hypertension
Journal of Diabetes Investigation Nov 10, 2017
Kimura T, et al. - Here, the authors compared the effects of sodium-glucose co-transporter 2 (SGLT2) inhibitor and thiazide diuretic on blood pressure, metabolic parameters and body mass composition. In subjects with type 2 diabetes and hypertension, switching from thiazide diuretic to an SGLT2 inhibitor ipragliflozin markedly improved various metabolic parameters and body mass composition without affecting blood pressure.
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