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Survival impact of pre-treatment neutrophils on oropharyngeal and laryngeal cancer patients undergoing definitive radiotherapy

Journal of Translational Medicine Aug 10, 2017

Sumner WA, et al. – In this study, the physicians included head and neck squamous cell carcinoma (HNSCC) patients to explore the relationship of the lymphocyte and neutrophil counts, the neutrophil–to–lymphocyte ratio (NLR) overall survival (OS), cancer–specific survival (CSS), local control (LC) and distant control (DC). They concluded that a higher pre–treatment neutrophil count correlates to poor OS, CSS, and DC. Lymphocyte counts were not found to impact survival or tumor control. Moreover, higher pre–treatment NLR was prognostic of poor OS.
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