Tajiri K, et al. - In this multicenter, retrospective, observational study, the researchers assessed the effects of tolvaptan treatment on survival of patients with decompensated liver cirrhosis with refractory ascites. Study participants were patients with cirrhosis who were treated with tolvaptan for hepatic ascites refractory to conventional diuretics. The findings from the present study suggested that the maintenance of renal function was essential in enhancing survival of patients with cirrhosis. During tolvaptan treatment, doses of diuretics should be adjusted appropriately.