Hsiue PP, Kelley BV, Chen CJ, et al. - This study epidemiologic study applied a large, nationally representative database to explore the trends, patient outcomes, and health-care resource utilization associated with surgical treatment of metastatic spine disease (MSD). Researchers recruited all individuals in the nationwide readmissions database (NRD) between 2010 and 2014 who had undergone spinal surgery. They examined mortality, blood transfusion, complications, length of stay, cost, and discharge location during index hospitalization as well as hospital readmission and revision surgery within 90-days of surgery. They distinguished patients of interest within the NRD between 2010 and 2014 using international Classification of Diseases, Ninth Revision, (ICD-9) codes. The study indicated that number of MSD individuals who undergo surgical treatments is increasing. It was demonstrated that not only do these individuals have worse results during index hospitalization, but they are also at an improved risk of hospital readmission for surgical site infection and neurologic complications. These data stress the requirement for multidisciplinary perioperative treatment plans that mitigate risks and facilitate quick, effective recovery in these unique, at-risk patients.