Lee JS, et al. - This trial was designed to determine if body composition parameters could predict radiographic progression-free survival (RFS) and cancer-specific survival (CSS) among patients with castration-resistant prostate cancer (CRPC). Higher RFS and CSS rates were demonstrated among patients with a subcutaneous fat index (SFI) ≥39.9 cm²/m² at the time of CRPC diagnosis compared to patients with a SFI <39.9 cm²/m². SFI estimated by computed tomography data was shown to be a beneficial objective prognostic factor for investigating therapeutic options.