Turkovic L, Caudri D, Rosenow T, et al. - Given that identification as well as management of structural lung disease could be a crucial step in enhancing results in cystic fibrosis (CF) patients, so, researchers undertook this study with annual chest computed tomography (CT) scans available from 2005 to 2016 as a part of AREST CF cohort for children aged 3-months to 6-years. They also analyzed the available annual spirometry measurements. They found that the probability of having abnormal FEV₁ during the next 10 years was more among children with a total CT score at 5–6 years above the median vs those below the median chest CT score. Overall, chest CT enabled the identification of children at an early age who had adverse long-term results. Early intervention should be focused on preventing structural lung damage. Chest CT could usefully evaluate structural lung damage. Chest CT could afford an early readout of likely long-term success in an era of therapeutics that might change disease trajectories.