Yang Z, et al. - Via a cohort study involving 80,442 individuals with first ischemic stroke between 2000 and 2014 through Clinical Practice Research Datalink, experts assessed secular trends and factors associated with statin use and dose following ischemic stroke. An elevation from 25% in 2000 to 70% in 2006 in the proportion of people using statins within 2 years after stroke was observed; however, it continued at about 75% through 2014. High-intensity utilization accounted for ~15% between 2004 and 2011 and then progressed to almost 35% in 2014 among post-stroke statin users. Patients aged ≥ 75 years, younger patients aged < 45 years, and patients with no prior statin treatment, dementia, underweight, or absence of cardiovascular factors were less likely to use statins and less likely to receive a high-intensity statin. Overall, investigators noted an increase over time in both statin use and dose, but many patients with ischemic stroke continue to be under-treated. Clinical trials and policy interventions to improve appropriate post-stroke statin use should, therefore, focus on younger and older patients, patients with no pre-stroke statin treatment, and patients without additional cardiovascular risk factors, based on the study findings.